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Challenger, the second orbiter to become operational at Kennedy Space Center, was named after the British Naval research vessel HMS Challenger that sailed the Atlantic and Pacific oceans during the 1870's. The Apollo 17 lunar module also carried the name of Challenger. Like her historic predecessors, Space Shuttle Challenger and her crews made significant contributions to America's scientific growth.
Challenger joined NASA fleet of reusable winged spaceships in July 1982. It flew nine successful Space Shuttle missions. On January 28, 1986, the Challenger and its seven-member crew were lost 73 seconds after launch when a booster failure resulted in the breakup of the vehicle.

Challenger started out as a high-fidelity structural test article (STA-099). The airframe was completed by Rockwell and delivered to Lockheed Plant 42 for structural testing on 02/04/78. The orbiter structure had evolved under such weight-saving pressure that virtually all components of the air frame were required to handle significant structural stress. With such an optimized design, it was difficult to acurately predict mechanical and thermal loading with the computer software available at the time. The only safe approach was to submit the structural test article to intensive testing and analysis. STA-099 underwent 11 months of intensive vibration testing in a 43 ton steel rig built especially for the Space Shuttle Test Program. The rig consisted of 256 hydraulic jacks, distributed over 836 load application points. Under computer control, it was possible to simulate the expected stress levels of launch, ascent, on-orbit, reentry and landing. Three 1 million pound-force hydraulic cylinders were used to simulate the thrust from the Space Shuttle Main Engines. Heating and thermal simulations were also done.

Rockwell's original $2.6 billion contract had authorized the building of a pair of static-test articles (MPTA-098 and STA-099 and two initial flight-test vehicles (OV-101 and OV-102. A decision in 1978 not to modify Enterprise from her Approach and Landing Test (ALT) configuration would have left Columbia as the only operational orbiter vehicle so on 1/29/79 NASA awarded Rockwell a supplemental contract to convert Challenger (STA-099) from a test vehicle into a space-rated Orbiter (OV-099).